Friend Erythroleukaemia Cell Mutants Defective in Viral Gene Expression
نویسندگان
چکیده
منابع مشابه
Isolation of poliovirus 2C mutants defective in viral RNA synthesis.
Two poliovirus mutants were isolated that contain an oligonucleotide linker insertion in the 2C-coding region of the viral genome. One, 2C-31, has a strongly temperature-sensitive phenotype and the other, 2C-32, forms small plaques on HeLa cell monolayers at all temperatures. Both mutants have a severe temperature-sensitive defect in viral RNA synthesis but little effect on the types of viral p...
متن کاملStudy the Expression of marA Gene in Ciprofloxacin and Tetracycline Resistant Mutants of Esherichia coli
MarA activates two membrane dependent mechanisms of resistance to different antibiotics, such as ciprofloxacin and tetracycline, including promotion of outflux and inhibition of influx of antibiotics. Thus, MarA causes multiple antibiotic resistance phenotype. The activation of these mechanisms needs overexpression of marA. This could happen through mutation in marR. Thus, the aim of this study...
متن کاملStudy the Expression of marA Gene in Ciprofloxacin and Tetracycline Resistant Mutants of Esherichia coli
MarA activates two membrane dependent mechanisms of resistance to different antibiotics, such as ciprofloxacin and tetracycline, including promotion of outflux and inhibition of influx of antibiotics. Thus, MarA causes multiple antibiotic resistance phenotype. The activation of these mechanisms needs overexpression of marA. This could happen through mutation in marR. Thus, the aim of this study...
متن کاملA Friend of Defective Children
deeply regret to record, to failing health, it is fitting that a tribute should be paid in these pages to the unselfish and devoted service of defective children which she has given over a period of nearly 20 years. It was in 1919, that she opened, in the King's Cross district of London, supported by a small Committee, the Lilian Greg Occupation Centre for lowgrade " ineducable " children, at a...
متن کاملICP27 phosphorylation site mutants are defective in herpes simplex virus 1 replication and gene expression.
Herpes simplex virus 1 (HSV-1) protein ICP27 is a multifunctional regulatory protein that is posttranslationally modified by phosphorylation during viral infection. ICP27 has been shown to be phosphorylated on three serine residues, specifically serine residues 16 and 18, which are within casein kinase 2 (CK2) sites, and serine residue 114, which is within a protein kinase A (PKA) site. Phospho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1984
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-65-2-429